Robert C. Alaniz, Ph.D.
Director College of Medicine Cell Analysis Facility (COM-CAF)
Education and Training
B.S., Texas A&M University (1991)
Ph.D., University of Washington – Immunology (2002)
Post-Doc, University of Washington – Microbial Pathogenesis (2007)
The overarching research goals of the lab are directed toward understanding important host and microbial mechanisms that instruct the development of pathogen-specific effector, memory, and protective T-cell immunity after infection with intracellular bacteria.
As our primary model, we use murine infection with Salmonella enterica Serovar typhimurium. Salmonellae are naturally acquired by the oral route and invade early after infection from the intestinal lumen through M-cells into the Peyer’s Patches. Afterward, Salmonella disseminates systemically to colonize peripheral tissues (e.g., the spleen).