Harrison, L.M., C. van den Hoogen, W.C.E. van Haaften, and V.L. Tesh. Chemokine expression in the monocytic cell line THP-1 in response to purified Shiga toxin 1 and/or lipopolysaccharides. Infection and Immunity 73:403-412 (2005).

Harrison, L.M., R.P. Cherla, C. van den Hoogen, W.C.E. van Haaften, S.-Y. Lee, and V.L. Tesh.  Comparative evaluation of apoptosis induced by Shiga toxin 1 and/or lipopolysaccharides in human monocytic cells and macrophage-like cells. Microbial Pathogenesis 38:11-24 (2005).

Lee, S.-Y., R.P. Cherla, I. Caliskan, and V.L. Tesh. Shiga toxin 1 induces apoptosis in the human myelogenous leukemia cell line THP-1 by a caspase 8-dependent, TNF receptor-independent mechanism. Infection and Immunity 73:5115-5126 (2005).

Clayton, F., T.J. Pysher, R. Lou, D.E. Kohan, N.D. Denkers, V.L. Tesh, F.B. Taylor, Jr., and R.L. Siegler. Lipopolysaccharide up-regulates renal Shiga toxin receptors in a primate model of hemolytic uremic syndrome. American Journal of Nephrology 25:536-540 (2005).

Siegler, R.L., T.J. Pysher, V.L. Tesh, M. Noris, P. Cassis, and F.B. Taylor, Jr. Reduced nitric oxide bioavailability in a baboon model of Shiga toxin mediated hemolytic uremic syndrome (HUS). Renal Failure 27:635-641 (2005).

Cherla, R.P., S.-Y. Lee, P.L. Mees, V.L. Tesh. Shiga toxin 1 induced cytokine production is mediated by MAP kinase pathways and translation initiation factor eIF4E in the macrophage-like THP-1 cell line. Journal of Leukocyte Biology 79:397-407 (2006).

DeCaluwe, H., L.M. Harrison, M.M. Mariscalco, D. Gendrel, C. Bohuon, V.L. Tesh, F. Proulx. Pro-calcitonin in children with Escherichia coli O157:H7-associated hemolytic uremic syndrome. Pediatric Research 59:579-583 (2006).

Lee, S.-Y., R.P. Cherla, and V.L. Tesh. Simultaneous induction of apoptotic and cell survival signaling pathways in macrophage-like THP-1 cells by Shiga toxin 1. Infection and Immunity 75:1291-1302 (2007).

Proulx, F., and V.L. Tesh. Renal diseases in the Pediatric Intensive Care Unit: thrombotic micro-angiopathy, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. In: Pediatric Critical Care Medicine: Basic Science and Clinical Evidence. D.S. Wheeler, H.R. Wong, and T.P. Shanley (eds.) Springer Verlag, London, UK. pp. 1189-1204 (2007).

Lee, S.-Y., M.-S. Lee, R.P. Cherla and V.L. Tesh. Shiga toxin 1 induces the ER stress response in human monocytes. Cellular Microbiology 10:770-780 (2008).

Cherla, R.P., S.-Y. Lee, R.A. Mulder, M.-S. Lee and V.L. Tesh. Shiga toxin 1-induced proinflammatory cytokine production is regulated by the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling pathway. Infection and Immunity 77:3919-3931 (2009).

Lee, M.-S., R.P. Cherla, D. Leyva-Illades, and V.L. Tesh. Bcl-2 regulates the onset of Shiga toxin 1-induced apoptosis in THP-1 cells. Infection and Immunity 77:5233-5244 (2009).

Tesh, V.L. The induction of apoptosis by Shiga toxins. Future Microbiology 5: 431-453 (2010).

Stearns-Kurosawa, D.J., V. Collins, S. Freeman, V.L. Tesh, and S. Kurosawa. Distinct physiologic and inflammatory responses elicited in baboons after challenge with Shiga toxin type 1 or 2 from enterohemorrhagic Escherichia coli. Infection and Immunity 78: 2497-2504 (2010).

Leyva-Illades, D., R.P. Cherla, C. Galindo, A.K. Chopra, and V.L. Tesh. The global transcriptional response of macrophage-like THP-1 cells to Shiga toxins. Infection and Immunity 78: 2454-2465 (2010).

Lee, M.-S., R.P. Cherla, and V.L. Tesh. Shiga toxins: intracellular trafficking to the ER leading to activation of host cell stress responses. Toxins 2: 1515-1535 (2010).

Lee, M.-S., R.P. Cherla, E.K. Lentz, D. Leyva-Illades, and V.L. Tesh. Signaling through C/EBP homologous protein and death receptor 5 and calpain activation differentially regulate THP-1 cell maturation-dependent apoptosis induced by Shiga toxin type 1. Infection and Immunity 78: 3378-3391 (2010).

Lentz, E.K., R.P. Cherla, V. Jaspers, B.R. Weeks, and V.L. Tesh. Role of TNF-α in disease using a mouse model of Shiga toxin-mediated renal damage.  Infection and Immunity 78: 3689-3699 (2010).

Lentz, E.K., R.P. Cherla, M.-S. Lee, and V.L. Tesh. Differential response of the human renal proximal tubular epithelial cell line HK-2 to Shiga toxin types 1 and 2. Infection and Immunity 79: 3570-3580 (2011).

Lee, M.-S., R.P. Cherla, M.H. Jenson, D. Leyva-Illades, M. Martinez-Moczygemba and V.L. Tesh. Shiga toxins induce autophagy leading to differential signaling pathways in toxin-sensitive and toxin-resistant human cells. Cellular Microbiology 13: 1479-1496 (2011).

Tesh, V.L. Activation of cell stress responses by Shiga toxins. Cellular Microbiology 14: 1-9 (2012).

Zhang, Y., G. Zhang, L. R. Hendrix, V.L. Tesh, and J.E. Samuel. Coxiella burnetii induces apoptosis during early stage infection via a caspase-independent pathway in human monocytic THP-1 cells. PLoS ONE 7(1):e30841 (2012)

Tesh, V.L. The induction of apoptosis Shiga toxins and ricin. Current Topics in Microbiology and Immunology 357: 137-178 (2012).

Leyva-Illades, D., R.P. Cherla, M.-S. Lee, and V.L. Tesh. Dual specificity phosphatase expression and its effect on mitogen-activated protein kinases and chemokine expression elicited by Shiga toxin type 1. Infection and Immunity 80: 2109-2120 (2012).

Stearns-Kurosawa, D.J., S.-Y. Oh, R.P. Cherla, M.-S. Lee, V.L. Tesh, J. Papin, J. Henderson, and S. Kurosawa. Distinct renal pathology and chemotactic phenotype after challenge with enterohemorrhagic Escherichia coli Shiga toxins in non-human primate models of hemolytic uremic syndrome. American Journal of Pathology 182: 1227-1238 (2013).

Lee, M.-S., M.H. Kim, and V.L. Tesh. Shiga toxins expressed by human pathogenic bacteria induce immune responses in host cells. J. Microbiol. 51(6): 724-730 (2013).

Lee, M.-S., R.P. Cherla, and V.L. Tesh. Chapter 45: Shiga toxin and Shiga-like ribosome-inactivating proteins. In: Manual of Security Sensitive Microbes and Toxins. D. Liu (ed.) Taylor and Francis Publishers, London, United Kingdom. pp. 519-532 (2014).

Lee, M.-S., H. Kwon, E.-Y. Lee, D.-J. Kim, V.L. Tesh, T.-K. Oh, and M.H. Kim. Shiga toxins activate the NLRP3 inflammasome pathway to promote both production of proinflammatory cytokine interleukin-1β and apoptotic cell death. Infection and Immunity – in review (2015).

Lee, M.-S., S.-H. Jo, D.H. Lee, C.M. Ryu, V.L. Tesh, and J.M. Park. Interaction of the human pathogenic bacteria Shigella with Arabidopsis thaliana. In Preparation (2015)