David N. McMurray, Ph.D.
Ph.D., 1972, University of Wisconsin-Madison
Postdoctoral, Tulane University International Center for Medical Research
One major research focus has been the impact of vaccination and nutritional status on immune responses and infectious disease resistance in a highly relevant guinea pig model of low-dose pulmonary tuberculosis (TB). Protein-deprived guinea pigs exhibit many of the metabolic and clinical hallmarks of kwashiorkor in humans. In many papers published over the past 35 years, with continual funding from NIH, we have dissected the detrimental impact of diet on mechanisms of vaccine-induced resistance of guinea pigs to pulmonary TB.