Welcome to Dr. Irtisha Singh’s Laboratory

Understanding Gene Regulation in Cancer Biology and Regenerative Medicine

Welcome to the Singh Lab! We are located in the Department of Molecular and Cellular Medicine, College of Medicine, Texas A&M Health Science Center. The primary goal of our laboratory is to model and understand the molecular basis of tumor development, progression, and response to therapy. Our laboratory applies and develop computational, molecular, and chemical biology approaches to understand mechanisms of transcriptional deregulation in cancer and the consequences of targeting the chromatin and transcription apparatus on cancer cell state. A parallel focus of our laboratory is to develop and use cellular engineered models of cancer cell state to discern the role of tumor microenvironment supporting neoplastic transformation. This integrated approach brings together a range of seemingly disparate disciplines that will address some of the complexity associated with cancer bioengineering and regenerative medicine in a manner that is otherwise not possible.

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