Publications

  1. Kumaravel S, Singh S, Venkatasamy S, White T, Sinha S, Glaser S, Safe S, Chakraborty S CXCL11-CXCR3 axis mediates tumor lymphatic crosstalk and inflammation induced tumor promoting pathways in head and neck cancers. 2019. Am J Pathology-(Accepted).
  2. Roy S, Glaser S and Chakraborty S. Inflammation and progression of cholangiocarcinoma: Role of angiogenic and lymphangiogenic mechanisms. 2019. Frontiers in Medicine (In Press).
  3. Lee Y, Chakraborty S, Meininger CJ, Muthuchamy M. Insulin resistance disrupts cell integrity, mitochondrial function and inflammatory signaling in lymphatic endothelium. Microcirculation. 2018 Jul 19: e12492. doi: 10.1111/micc.12492. PMID:30025187.
  4. Kim J*, Chakraborty S*, Jayaprakasha GK, Muthuchamy M, Patil BS. Citrus nomilin down-regulates TNF-α-induced proliferation of aortic smooth muscle cells via apoptosis and inhibition of IκB. Eur J Pharmacol. 2017 May 24. pii:S0014-2999(17)30374-6. doi: 10.1016/j.ejphar.2017.05.043. [Epub ahead of print] PubMed PMID: 28551013. (*first author equal contribution).
  5. Y Lee, J.D Fluckey, S. Chakraborty*, M. Muthuchamy*. Hyperglycemia and hyperinsulinemia induced insulin resistance causes alterations in cellular bioenergetics and activation of inflammatory signaling in lymphatic muscle. FASEB J. 2017 Mar 15. pii: fj.201600887R. doi: 10.1096/fj.201600887R (* corresponding author: equal contribution).
  6. Zawieja SD, Wang W, Chakraborty S, Zawieja DC, Muthuchamy M. Macrophage alterations within the mesenteric lymphatic tissue are associated with impairment of lymphatic pump in metabolic syndrome Microcirculation. 2016 Sep 2. doi: 10.1111/micc.12307.
  7. Chakraborty S, Zawieja S, Wang W, Zawieja DC and Muthuchamy M. “Lipopolysaccharide modulates neutrophil recruitment and macrophage polarization on lymphatic vessels and impairs lymphatic function in rat mesentery” Am J Physiol Heart Circ Physiol. 2015 Oct 9:ajpheart.00467.2015. doi: 10.1152/ajpheart.00467.2015. PMID: 26453331.
  8. Chakraborty S, Zawieja DC, Davis MJ and Muthuchamy M. MicroRNA Signature of Inflamed Lymphatic Endothelium and Role of miR-9 in Lymphangiogenesis and Inflammation. Am J Physiol Cell Physiol. 2015 Nov 15; 309(10):C680-92. doi: 10.1152/ajpcell.00122.2015. PMCID: PMC4652079.
  9. Chakraborty S, Davis MJ, Muthuchamy M Emerging trends in the pathophysiology of lymphatic contractile function Semin Cell Dev Biol. 2015 Jan. pii: S1084-9521(15) 00007-5. doi: 10.1016/j.semcdb.2015.01.005.
  10. Dougherty PJ, Nepiyushchikh ZV, Chakraborty S, Wang W, Davis MJ, Zawieja DC, Muthuchamy M. PKC activation increases Ca2+ sensitivity of permeabilized lymphatic muscle via myosin light chain 20 phosphorylation-dependent and -independent mechanisms. Am J Physiol Heart Circ Physiol. 2014 Mar; 306(5): H674-83. doi: 10.1152/ajpheart.00732.2013. PMID: 24414065; PMCID: PMC3949071.
  11. Chakraborty S, Guruswamy M, Zawieja DC, Muthuchamy M. Lymphatic filariasis: perspectives on lymphatic remodeling and contractile dysfunction in filarial disease pathogenesis. Microcirculation. 2013 Jul; 20(5): 349-64. doi: 10.1111/micc.12031. PMID 23237232; PMCID: PMC3613430.
  12. Nepiyushchikh ZV, Chakraborty S, Wang W, Davis MJ, Zawieja DC, Muthuchamy M. Differential effects of myosin light chain kinase inhibition on contractility, force development and myosin light chain 20 phosphorylation of rat cervical and thoracic duct lymphatics. J Physiol. 2011 Nov 15;589(Pt 22):5415-29. doi: 10.1113/jphysiol.2011.281446. PMID: 21930597; PMCID: PMC324088.
  13. Chakraborty S, Nagashri MN, Mohiyuddin SM, Gopinath KS, Kumar A. Gene expression profiling of oral cancer by differential display RT-PCR. Indian J Surg Oncol, 2010 Dec; 1(4): 284-93. doi: 10.1007/s13193-011-0054-x. PMID: 22693380; PMCID: PMC3244262.
  14. Chakraborty S, Nepiyushchikh Z, Davis MJ, Zawieja DC, Muthuchamy M. Substance P activates both contractile and inflammatory pathways in lymphatics through the neurokinin receptors NK1R and NK3R. Microcirculation. 2011 Jan;18(1):24-35. doi: 10.1111/j.1549-8719.2010.00064.x. PMID: PMCID: PMC3058475.
  15. Wu X, Chakraborty S, Meininger GA, Davis MJ, Muthuchamy M. Fibronectin increases the force production of mouse papillary muscles via 51 integrin. J Mol Cell Cardiol. 2011 Jan; 50(1):203-13. doi: 10.1016/j.yjmcc.2010.10.003. PMID: 20937283; PMCID: PMC3019265.
  16. Chakraborty S, Zawieja S, Wang W, Zawieja DC, Muthuchamy M. Lymphatic system: a vital link between metabolic syndrome and inflammation. Ann N Y Acad Sci. 2010 Oct;1207 Suppl 1: E94-102. doi: 10.1111/j.1749-6632.2010.05752.x. PMID: 20961312; PMCID: PMC2965625.
  17. Wang W*, Nepiyushchikh Z*, Zawieja DC, Chakraborty S, Zawieja SD, Gashev AA, Davis MJ, Muthuchamy M. Inhibition of myosin light chain phosphorylation decreases rat mesenteric lymphatic contractile activity. Am J Physiol Heart Circ Physiol. 2009 Aug; 297(2):H726-34. doi: 10.1152/ajpheart.00312.2009. PMID: 19525378; PMCID: PMC2724206.
  18. Chakraborty S, Mohiyuddin SM, Gopinath KS, Kumar A. Involvement of the TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma. BMC Cancer. 2008 Jun 6;8:163. doi: 10.1186/1471-2407-8-163. PMID: 18538015; PMCID: PMC2430211.
  19. Kumar A, Dorairaj SK, Prabhakaran VC, Prakash DR, Chakraborty S. Identification of genes associated with tumorigenesis of meibomian cell carcinoma by microarray analysis. Genomics. 2007 Nov;90(5):559-66. PMID: 17889501.
  20. Chakraborty S, Khare S, Dorairaj SK, Prabhakaran VC, Prakash DR, Kumar A. Identification of genes associated with tumorigenesis of retinoblastoma by microarray analysis. Genomics. 2007 Sep; 90(3): 344-53. PMID: 17604597