Sengupta, D., Koblansky, A., Gaines J., Brown T., West PA, Zhang D., Nishikawa T., Park., Roop MR., Ghosh S. Subversion of innate immune responses byBrucella through the targeted degradation of the TLR signaling adapter, MAL. J Immunol. 2010 Jan 15;184(2):956-64. PMID: 20018612
Cai Z, Shi Z, Sanchez A, Zhang T, Liu M, Yang J, Wang F, Zhang D.*Transcriptional regulation of TLR11 gene expression in epithelial cells. J Biol Chem. 2009 Nov 27;284(48):33088-96. Epub 2009 Oct 2. PMID: 19801549 .
Fan Y, Mao R, Zhao Y, Yu Y, Sun W, Song P, Shi Z, Zhang D, Yvon E, Zhang H, Fu S, Yang J. Tumor necrosis factor-[alpha] induces RelA degradation via ubiquitination at LYS-195 to prevent excessive nuclear factor-[kappa]B activation. J Biol Chem. 2009 Oct 23;284(43):29290-7. Epub 2009 Aug 25. PMID: 19706600 .
Shi Z, Cai Z, Wen S, Chen C, Gendron C, Sanchez A, Patterson K, Fu S, Yang J, Wildman DE, Finnell RH, Zhang D* Transcription regulation of the novel Toll-like receptor TLR13. J Biol Chem. 2009 Jul 31;284(31):20540-7. Epub 2009 Jun 1. PMID: 19487701
Sun W, Yu Y, Dotti G, Shen T, Tan X, Savoldo B, Pass AK, Chu M, Zhang D, Lu X, Fu S, Lin X, Yang J. PPM1A and PPM1B Act as IKKbeta Phosphatases to terminate TNFalpha-induced NF-kappaB activation. Cell Signal. 2009 Jan;21(1):95-102. Epub 2008 Oct 1.
Cai Z. and Zhang D.* Toll-like receptor and cancer Int J Genet. Aug. 15 2008, Vol 31(4): 275-281.
Yu Y, Ge N, Xie M, Sun W, Burlingame S, Pass AK, Nuchtern JG, Zhang D, Fu S, Schneider MD, Fan J, and Yang Y, Phosphorylation of Thr-178 and Thr-184 in TAK1 T-loop is required for interleukin (IL)-1-mediated optimal NF-κB and AP-1 activations as well as IL-6 gene expression. J Biol Chem. 2008 Sep 5;283(36):24497-505. Epub 2008 Jul. PMID: 18617512
Huang X, Shi Z, Wang W, Bai J, Chen Z, Xu J, Zhang D, Fu S. Identification and characterization of a novel protein ISOC2 that interacts with p16(INK4a).BBRC. 2007 Sep 21; 361(2):287-93. Epub 2007 Jul 16. PMID: 17658461
Yarovinsky F., Zhang D., Andersen J., Bannenberg GL., Serhan C., Hieny S., Flavell RA., Ghosh S., Sher A. TLR11 activation of dendritic cells by a protozoan profilin-like protein. Science 2005 Jun 10; 308(5728):1626-9. PMID: 15860593
Zhang D., Zhang GL, Hayden MS, Greenblatt M, Bussey C., Flavell R., and Ghosh S. A novel Toll-like receptor that prevents infection by uropathogenic bacteria. Science. 2004 Mar 5; 303(5663):1522-6. PMID: 15001781 (Highly cited) www.esi-topics.com/nhp/2005/may-05-Ghosh_Hayden_Zhang.html
Cao D., Russell R., Zhang D., Leffert J., and Pizzorno G. Uridine phosphorylase (-/-) murine embryonic stem cells clarify the key role of this enzyme in the regulation of the pyrimidine salvage pathway and in the activation of fluoropyrimidines. Cancer Res. 2002; 62(8):2313-7. PMID: 11956089
Pizzorno G, Cao D, Leffert JJ, Russell RL, Zhang D.K., Handschumacher RE Homeostatic control of uridine and the role of uridine phosphorylase: a biological and clinical update. Biochim Biophys Acta. 2002, 1587(2-3):133-44. PMID: 12084455
Zhang D., Cao D., Russell R., and Pizzorno G. p53-dependent Suppression of Uridine Phosphorylase Gene Expression through Direct Promoter Interaction.Cancer Res. 2001 61: 6899-6905.
Russell RL, Cao D, Zhang D., Handschumacher RE, Pizzorno G. Uridine phosphorylase association with vimentin. Intracellular distribution and localization. J Biol Chem. 2001; 276(16):13302-7.
Yang X, Sham JS, Ng MH, Tsao SW, Zhang D., Lowe SW, Cao L. LMP1 of Epstein-Barr virus induces proliferation of primary mouse embryonic fibroblasts and cooperatively transforms the cells with a p16-insensitive CDK4 oncogene. J Virol. 2000; 74(2):883-91.
Cao DL, Immakayalu MA, Wang FY, Zhang D., Handschumacher RE, Bray-Ward P, Pizzorno G., Genomic structure, chromosomal mapping, and promoter region analysis of murine uridine phosphorylase gene. Cancer Res. 1999, 59:4997-5001.
Zhang D., Ngan H.Y.S., Cheng R.Y.S., Cheung A.N.Y., Liu S.S., and Tsao S.W., Clinical significance of telomerase activity and telomeric restriction fragment (TRF) in cervical cancer. Eur J Cancer. 1999; 35(1):154-60.
Tu W, Zhang D., Cheung PT, Tsao SW, Lau YL. Effect of insulin-like growth factor 1 on PHA- stimulated cord blood mononuclear cell telomerase activity.Br J Haematol. 1999;104(4):785-94.
Cheug ANY, Zhang D., Liu Y, Nga HYS, Shen DH, Tsao SW. Telomerase activity in gestational trophoblastic disease. J of Clin Pathology 1999; 52(8): 588-592.
Choo CK, Ling MT, Chan KW, Tsao SW, Zheng Z, Zhang D., Chan LC, Wong YC. Immortalization of human prostate epithelial cells by HPV 16 E6/E7 open reading frames. Prostate 1999; 40(3):150-8.
Litaker JR, Pan J, Cheung Y, Zhang D., Liu Y, Wong SC, Wan TS, Tsao SW. Expression profile of senescence-associated beta-galactosidase and activation of telomerase in human ovarian surface epithelial cells undergoing immortalization. Int J Oncol. 1998; 13(5):951-6.
Tsao S.W., Zhang D.K., Cheng R.Y.S., Wan T.S.K., Telomerase activation in human cancers. Chinese Medical J., 1998; 111(8): 745-750.
He D., Zhang D., Lam K.Y., Ma L., Ngan H.Y.S., Liu S.S., and Tsao S.W., Prevalence of HPV infection in esophageal squamous cell carcinoma in Chinese patients and its relationship to the p53 gene mutation. Int. J. Cancer. 1997;72: 959-964.
Lam K.Y., Tsao S.W., Zhang D., Law S., He D., Ma L. and Wong J., Prevalence and predictive value of p53 mutation in patients with esophageal squamous cell carcinomas: a prospective clinic-pathological study and survival analysis of 70 patients. Int. J. Cancer. 1997; 74: 212-219.
Lam K.Y., Dan He, Ma L., Zhang D., Ngan H.Y.S., Wan T.S.K., and Tsao S.W., Presence of human papillomavirus in esophageal squamous cell carcinomas of Hong Kong Chinese and its relationship with p53 gene mutation. Hum Pathol. 1997; 28 (6), 657-663.
Zhang D., Z. Zhang, Molecular genetics study on human cervical cancer. Int J Genet. 1:20-23 (1995).
Zhang D., Wang W., and G.Y. Zhang. Loss of heterozygosity for alleles in gastric cancer. Medical Biology Study of China. 1995; 1,249-250.
Zhang D., AT Zhang, ZK Zhang, GY Zhang, X. Zhang and KL Sun, Study p53 gene mutation in human primary gastric cancer. J. Chinese Med Genetics. 1993; 10(6): 236-238.
X. Zhang, Zhang D. and KL Sun, p53 gene mutation in primary liver cancer. J China Med Univ. 1993; 5:330-333.
Zhang D., The inheritance of primary spontaneous pneumothorax. Int J Genet. 1992; 2:97-99.
Zhang D., and AT Zhang, Advances in molecular genetics in human gastric cancer. Int J Genet. 1992; 2:65-68.
Zhang D., and AT Zhang, Potential contributions of genetic epidemiology. Int J Genet. 1989; 4:196-198.